Milwaukee is the largest city in the state of Wisconsin and the fifth-largest city in the Midwestern United States. The seat of Milwaukee County, the city is located on Lake Michigan's southwestern shore and was incorporated in 1846. As of the U.S. Census Bureau's July 1, 2019 estimate, Milwaukee had a population of 590,157, making it the 31st largest city in the United States and the fourth-largest city situated along one of the Great Lakes. It is the main cultural and economic center of the Milwaukee metropolitan area, the fourth-most densely populated metropolitan area in the Midwest. Milwaukee is considered a "Gamma −" global city as categorized by the Globalization and World Cities Research Network with a regional GDP of over $107 billion.