Wall Street cruises toward Easter holiday, S&P 500 breaks 4K for the first time

12:25pm: Microsoft surges on US Army contract The Dow climbed steadily Thursday morning adding 162 points, 0.5%, to hit 33,144 in early afternoon trading. The Nasdaq Composite rose 207 points, 1.6%, to 13,453, and the S&P 500 picked up 38 points, 1%, to 4,011 — crossing the 4,000 threshold for the first time. Microsoft Corporation stock improved 2.2% to $241.05 on news that the company won a contract to build more than 120,000 augmented reality headsets for the US Army, according to media reports. 10:33am: Proactive North America headlines: GoviEx Uranium Inc (CVE:GXU) (OTCQB:GVXXF) (FRA:7GU) taps industry veteran Christopher Mark Lewis to head its uranium marketing efforts HealthLynked Corp (OTCQB:HLYK) touts significant revenue growth in 4Q, full year 2020 results as user base grows Bragg Gaming Group Inc (TSE:BRAG) OTCMKT:BRGGF) (FRA:SL4A) subsidiary ORYX Gaming to take its exclusive RGS content live across Dazzletag’s numerous brands PyroGenesis Canada Inc (TSE:PYR) (NASDAQ:PYR) (FRA:8PY)  swings to a profit in 2020 with $42M in earnings American Battery Metals Corporation (OTCQB:ABML) appoints tech sector veteran Nick Copping to its Advisory Board Pure Gold Mining Inc (CVE:PGM) (LON:PUR) (OTCMKTS:LRTNF) (FRA:L11A) hails positive ramp-up of Red Lake mine as it continues towards declaring commercial production Biocept Inc (NASDAQ:BIOC) (FRA:B003) to host webinar with leading neuro-oncologists to discuss its cerebrospinal fluid assay (CSF) for diagnosing and managing tumors Dalrada Financial Corp (OTCQB:DFCO) enters genomics market with subsidiary launch Tetra Bio-Pharma Inc (TSE:TBP) (OTCQB:TBPMF) (FRA:JAM1)  touts Health Canada notice of compliance after inspection of Reduvo cannabinoid soft gel capsules Todos Medical Ltd (OTCQB:TOMDF) installs automated lab equipment and completes training for New Jersey-based Meadowlands Diagnostics Nextleaf Solutions  Ltd (CSE:OILS) (OTCQB:OILFF) (FRA:L0MA)  secures C$3M in convertible note financing GlobeX Data Ltd (OTCQB:SWISF) (CSE:SWIS) (FRA:GDT) closes its C$1.2M private placement financing Los Andes Copper  Ltd (CVE:LA) (OTCMKTS:LSANF) (FRA:L41A) welcomes final results from pre-feasibility metallurgical testing on flagship Chile project CytoDyn Inc (OTCQB:CYDY) files new protocol with FDA for four doses of leronlimab for critically ill coronavirus patients 9:40am: Positive start The main indices on Wall Street got off to a positive start on Thursday as traders shrugged off a bigger than expected rise in jobless claims last week. In the early minutes of trading, the Dow Jones Industrial Average was up 0.35% at 33,097 while the S&P 500 climbed 0.69% to 4,000 and the Nasdaq rose 1.34% to 13,424. Optimism over Joe Biden’s infrastructure spending plans appear to have taken precedence over the jobless claims data, which showed that for the week to March 26, 719,000 Americans filed for unemployment benefits, up from 658,000 the week before and higher than analyst forecasts of 675,000. The US Department of Labor said: "The 4-week moving average was 719,000, a decrease of 10,500 from the previous week's revised average. This is the lowest level for this average since March 14, 2020 when it was 225,500. The previous week's average was revised down by 6,500 from 736,000 to 729,500." 8:00am: Wall Street to open higher US markets look like they are set for a positive start on Thursday, helped by President Biden's US$2trn infrastructure plan. The Dow Jones Industrial Average is expected to open 47 points or 0.14% higher at 32,981 after showing a decline on Wednesday (unlike the other two main indices). The S&P 500 is forecast to add to its rise with a 0.3% increase while the Nasdaq Composite is set to open 0.9% higher. Sophie Griffiths, market analyst at OANDA, said: "News that President Biden is ready to inject a further US$2trn into the US economy has been well received. The world’s largest economy will see the huge injection of cash improve roads, railways, broadband and clean energy, while being offset by a rise in corporate taxes. Investors are already pricing in the read-across effect, and a boost to the US economy is good news for the global economy." Further signs of the state of the world's biggest economy will come shortly with the US ISM manufacturing index, which is expected to come in at 61.5 for March, up from 60.8. Michael Hewson at CMC Markets UK said: "Particular attention [is] likely to be on both prices paid, which hit 86 last month, and a 12-year high, and the employment component, which rose to its highest level in two years. A strong number here would raise expectations further for a strong payrolls report, either tomorrow or in a months’ time." Before that are the latest weekly jobless claims. They are expected to fall to 675,000 from 684,000. Three things to watch for on Thursday: Entrants in the earnings calendar for Thursday include used car retailer CarMax Inc (NYSE:KMX), water supply group Consolidated Water Co (NASDAQ:CWCO) and wound care specialist Sanara Medtech Inc (NASDAQ:SMTI) Shares in Pfizer Inc (NYSE:PFE) will be back in the spotlight after the company unveiled new data for its COVID-19 vaccine Cannabis firm may also be in focus following the legalisation of the drug in New York, opening up another huge market for the sector