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Fact Check: No, former first lady Michelle Obama has not earned her Ph.D. in law

USATODAY.com Friday, 3 July 2020
The former first lady has been busy since leaving the White House, but claims that she's earned another degree are false.
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Michelle Obama Michelle Obama Lawyer, writer and former First Lady of the United States

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Doctor of Philosophy Doctor of Philosophy Postgraduate academic degree awarded by universities in many countries

Increased blood sugar levels likely to decrease benefits of aerobic exercise [Video]

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Aerobic exercises are well known for its many benefits for overall health. However, a team of scientists, from Joslin Diabetes Center now have discovered that some benefits of aerobic exercise may be dampened by higher-than-normal blood sugar levels, a condition is known as hyperglycemia. These diminished gains are seen in mouse models and humans with chronic hyperglycemia that is in the "prediabetes" range, said Sarah Lessard, PhD, a Joslin assistant investigator in the section of Clinical, Behavioral and Outcomes Research and senior author on a paper in Nature Metabolism that presents the work. The study also showed that this maladaptive trait is independent of obesity and insulin levels in the blood. Clinical studies have demonstrated that people with diabetes or chronically high levels of blood sugar struggle to improve their aerobic exercise capacity compared to people with normal blood sugar levels. The study also aimed to uncover the mechanisms that may lead to low fitness levels in people with hyperglycemia. Muscle tissue can remodel itself, which is one reason why exercise becomes easier when we do it regularly, Lessard says. Over time, aerobic exercise such as running or swimming can alter muscle fibres to become more efficient at using oxygen during exercise.

Credit: ANI    Duration: 01:32Published
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A team of investigators has uncovered a potentially promising strategy to target brain tumours -- isocitrate dehydrogenase (IDH) genes, which are the most common brain tumours diagnosed in younger adults aged 18 to 45 years. Led by investigators at Massachusetts General Hospital, the finding of their study are published in Cancer Discovery, a journal of the American Association for Cancer Research. Prior work by the group, led by Mass General's Daniel Cahill, MD, PhD, Hiroaki Wakimoto, MD, PhD, and Julie Miller, MD, PhD, revealed that IDH mutant gliomas have a metabolic weakness making them especially susceptible to treatments that lower NAD+ levels, a ubiquitous and vital metabolic molecule commonly thought of as the "currency of metabolism" in cells. Also, previous work by other researchers found that chemotherapy activates an enzyme that stimulates NAD+ molecules to join together to make poly (ADP-ribose), or PAR, a key DNA damage signal. This PAR signal is a known susceptibility in IDH mutant gliomas. Researchers also discovered that activation of the enzyme by chemotherapy causes available NAD+ to be critically depleted for the production of PAR in IDH mutant glioma cells, but not normal cells. These findings indicated that maintaining high PAR levels (and low NAD+ levels), in combination with chemotherapy, may uniquely target IDH mutant glioma cells. Considering this, Hiroaki Nagashima, MD, PhD, research fellow and lead author, devised a new treatment strategy and tested it in tumour cells and animal models.

Credit: ANI    Duration: 01:10Published

White House White House Official residence and workplace of the President of the United States

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