Designer Miuccia Prada, considered an industry trailblazer, presented a spring line she said was about "the power of women over clothing" dressing models in breezy dresses and sharp suits.
A grey sweater and lightweight white skirt opened the show.
There were brief nods to the 1920s with layered dresses and suits in dark colours or geometric patterns recalled the 1970s.
A leaf embroidery adorned coat, dresses and long pencil skirts showed off the theme while jewellery included shell necklaces and earrings.
Dresses were overall light, colourful ribbed knits came as halterneck tops and pencil skirts.
Black coats with white buttons were almost teacher-like.
Leather skirts were tied at the waist and dabs of brocade popped up on suits.
Trousers were wide-legged, worn with jackets with white buttons.
Heels, sandals, platforms, boots and flats as well as bonnet-like hats - colourful, golden or in snakeskin print - completed the looks with Prada's staple handbags.
Milan Fashion Week is the third leg in the month-long Spring/Summer 2020 catwalk run which began in New York and also includes London and Paris.
(Production: Jayson Mansaray)