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New Inflammatory Condition in Children Probably Linked to Coronavirus, Study Finds

NYTimes.com Wednesday, 13 May 2020
Researchers compared 10 cases in Italy with previous cases of a similar childhood illness, Kawasaki disease. The rate of the new cases was much higher, and the conditions were more serious.
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News video: 3 New Orleans-area children being treated for coronavirus-related condition

3 New Orleans-area children being treated for coronavirus-related condition 01:40

3 New Orleans-area children being treated for coronavirus-related condition

💡 One News Page Knowledge: Other News Mentions

Coronavirus Coronavirus Subfamily of viruses in the family Coronaviridae

AP Top Stories August 7 A

Here's the latest for Friday August 7th: Coronavirus relief deal talks described as close to collapsing; Mexico records 50,000 coronavirus deaths; Unlawful..
USATODAY.com

CBS Evening News, August 6, 2020

Coronavirus model projects U.S. death toll could hit 300,000 by December;
CBS News

'We're very far apart': Coronavirus relief negotiations left in uncertainty after Congress leaves for the weekend

Both sides push for a compromise by the end of the week, but progress on a deal has bogged down.

USATODAY.com
Alcoholism treatment is potentially effective against COVID-19 [Video]

Alcoholism treatment is potentially effective against COVID-19

A team of chemists from HSE University and the Zelinsky Institute of Organic Chemistry used molecular modelling to find out that two medications that have been known for a long time can be used to fight SARS-CoV-2. These are disulfiram, which is used to treat alcoholism, and neratinib, an experimental drug being used to treat breast cancer. The paper about the discovery has been published online in the 4th issue of Mendeleev Communications journal.The structural elements of the virus that are less subject to mutation during its evolution should be chosen as a target for the potential treatment. Otherwise, a medication effective against one strain would no longer be effective against another. The best candidates for this are conservative proteins, such as the SARS-CoV-2 virus main protease M pro. In addition to being resistant to mutations, M pro plays a major role in coronavirusreplication, which means that its inhibition (blocking its function) is able to slow down or even completely stop its reproduction inside the body.Usually, the process of docking, as with a port dock and a ship entering it, is used for molecular modelling in simple cases. Two molecules participate in docking. One is called a 'ligand' (here, it is a medicine), and the other one is 'receptor' (or active site) of the target protein, such as Mpro, which can be used to 'dock'. An effective drug docks with the active site, by covalent links, which makes the enzyme dysfunctional or destroys it. But classical docking does not work in SARS-CoV-2.To overcome this problem, chemists from HSE University and the Zelinsky Institute decided to use 'on-top docking', which they came up with shortly before the pandemic. 'We decided not to focus on the previously described active site, but to investigate the whole surface of M pro protein with many medications, hoping that the big calculation powers would return useful "dockings",' - said Igor Svitanko, the author of the article,Professor at the HSE Joint Department of Organic Chemistry with the RAS Zelinsky Institute of Organic Chemistry.

Credit: ANI    Duration: 01:10Published
Health experts warn U.S. cities of 'trouble ahead' [Video]

Health experts warn U.S. cities of 'trouble ahead'

White House health experts are warning of a slow rise in the percentage of people testing positive for coronavirus in U.S. cities such as Boston, Chicago, Detroit and Washington and urged local leaders to remain vigilant to avoid a surge. Lisa Bernhard produced this report.

Credit: Reuters - Politics    Duration: 02:19Published

Italy Italy Country in southern Europe

Tourist Posing For Photo Damages 19th Century Italian Sculpture

Here's what happens when doing it for the 'Gram goes wrong -- a tourist in Italy damaged a 200-year-old sculpture while posing for a pic. The tourist, who hails..
TMZ.com
Ferrari's new Roma coupe aims to take on Aston Martin and Mercedes [Video]

Ferrari's new Roma coupe aims to take on Aston Martin and Mercedes

A look at the Ferrari Roma, the Italian supercar maker's new four-seat GT car.

Credit: PA - Press Association STUDIO    Duration: 01:16Published

Tourist damages 200-year-old Italian sculpture while posing for a photo

An Austrian tourist broke several toes off of the original plaster of the 200-year-old sculpture, “Paolina Borghese as Venus Victrix,” at the Museo Antonio..
CBS News

For Liam Neeson and son, 'Made in Italy' was a family affair

Liam Neeson and son Micheal Richardson remember late wife and mother, Natasha Richardson. The two act opposite each other in new comedy drama, "Made in Italy."..
USATODAY.com
Italy inaugurates new bridge after deadly collapse [Video]

Italy inaugurates new bridge after deadly collapse

Italy inaugurated a new bridge in Genoa in place of one that collapsed and killed 43 people two years ago.View on euronews

Credit: euronews (in English)    Duration: 00:50Published

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