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Inside Johnson & Johnson’s Nonstop Hunt for a Coronavirus Vaccine

NYTimes.com Friday, 17 July 2020 ()
In Boston and in the Netherlands, scientists are racing to build a vaccine against the virus strangling the world.
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Video Credit: Reuters Studio - Published
News video: 'We're not there yet' - UK's Johnson on vaccine

'We're not there yet' - UK's Johnson on vaccine 01:21

British Prime Minister Boris Johnson said on Monday (July 20) he could not promise there would be successful vaccine against COVID-19 developed by the end of this year, saying "we're not there yet" even as Britain lines up supplies.

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Johnson & Johnson Johnson & Johnson U.S. multinational medical devices, pharmaceutical and consumer packaged goods manufacturer

'Cautious optimism' - J&J vaccine trials underway [Video]

'Cautious optimism' - J&J vaccine trials underway

With more than 20 COVID-19 vaccines in clinical trials, the collaboration between Johnson & Johnson and Beth Israel Deaconess in Boston is getting $1 billion in U.S. funding. Lead researcher Dan Barouch charts the road ahead. (Produced by Dan Fastenberg)

Credit: Reuters Studio    Duration: 01:10Published
J&J: Consumers Have Given Up On Skincare [Video]

J&J: Consumers Have Given Up On Skincare

On Thursday, Johnson & Johnson detailed it's quarterly earnings. The company said shoppers are not buying skincare and beauty products as more and more people remain isolated at home. Business Insider said the negative hit on skincare has cost the company 3.4% in terms of worldwide sales.

Credit: Wochit News    Duration: 00:30Published
Johnson & Johnson Cease Production Of Lightening Products [Video]

Johnson & Johnson Cease Production Of Lightening Products

The corporation behind Johnson's, Neutrogena, Clean & Clear, and more has just vowed to stop selling two lines of skin-care products used for skin-lightening overseas. On June 19, in the wake of the recent Black Lives Matter uprising, Johnson & Johnson said that it will cease production of two different lines from Asian and Middle Eastern markets that were used for skin-lightening lines.

Credit: Wochit News    Duration: 00:33Published

Coronavirus Coronavirus Subfamily of viruses in the family Coronaviridae

AP Top Stories August 7 A

Here's the latest for Friday August 7th: Coronavirus relief deal talks described as close to collapsing; Mexico records 50,000 coronavirus deaths; Unlawful..
USATODAY.com

CBS Evening News, August 6, 2020

Coronavirus model projects U.S. death toll could hit 300,000 by December;
CBS News

'We're very far apart': Coronavirus relief negotiations left in uncertainty after Congress leaves for the weekend

Both sides push for a compromise by the end of the week, but progress on a deal has bogged down.

USATODAY.com
Alcoholism treatment is potentially effective against COVID-19 [Video]

Alcoholism treatment is potentially effective against COVID-19

A team of chemists from HSE University and the Zelinsky Institute of Organic Chemistry used molecular modelling to find out that two medications that have been known for a long time can be used to fight SARS-CoV-2. These are disulfiram, which is used to treat alcoholism, and neratinib, an experimental drug being used to treat breast cancer. The paper about the discovery has been published online in the 4th issue of Mendeleev Communications journal.The structural elements of the virus that are less subject to mutation during its evolution should be chosen as a target for the potential treatment. Otherwise, a medication effective against one strain would no longer be effective against another. The best candidates for this are conservative proteins, such as the SARS-CoV-2 virus main protease M pro. In addition to being resistant to mutations, M pro plays a major role in coronavirusreplication, which means that its inhibition (blocking its function) is able to slow down or even completely stop its reproduction inside the body.Usually, the process of docking, as with a port dock and a ship entering it, is used for molecular modelling in simple cases. Two molecules participate in docking. One is called a 'ligand' (here, it is a medicine), and the other one is 'receptor' (or active site) of the target protein, such as Mpro, which can be used to 'dock'. An effective drug docks with the active site, by covalent links, which makes the enzyme dysfunctional or destroys it. But classical docking does not work in SARS-CoV-2.To overcome this problem, chemists from HSE University and the Zelinsky Institute decided to use 'on-top docking', which they came up with shortly before the pandemic. 'We decided not to focus on the previously described active site, but to investigate the whole surface of M pro protein with many medications, hoping that the big calculation powers would return useful "dockings",' - said Igor Svitanko, the author of the article,Professor at the HSE Joint Department of Organic Chemistry with the RAS Zelinsky Institute of Organic Chemistry.

Credit: ANI    Duration: 01:10Published
Health experts warn U.S. cities of 'trouble ahead' [Video]

Health experts warn U.S. cities of 'trouble ahead'

White House health experts are warning of a slow rise in the percentage of people testing positive for coronavirus in U.S. cities such as Boston, Chicago, Detroit and Washington and urged local leaders to remain vigilant to avoid a surge. Lisa Bernhard produced this report.

Credit: Reuters - Politics    Duration: 02:19Published

Boston Boston State capital of Massachusetts, U.S.


Netherlands Netherlands Country in Western Europe

Face Coverings, Social Distancing Can Reduce COVID-19 Spread By 65% [Video]

Face Coverings, Social Distancing Can Reduce COVID-19 Spread By 65%

Wearing a mask, social distancing, and regular handwashing could reduce the spread of COVID-19. In fact, it could reduce the spread by as much as 65%, according to reports at UPI. Researchers from the Netherlands also applaud government-imposed social distancing measures. This includes closure of non-essential businesses and "stay-at-home" orders. These moves could delay the peak of an epidemic by up to seven months.

Credit: Wochit News    Duration: 00:36Published
EU survives COVID talks but not unscathed [Video]

EU survives COVID talks but not unscathed

Tense recovery talks have revealed deep political fractures in the European Union, questioning its ability to stay unified. Megan Revell reports.

Credit: Reuters - Politics    Duration: 03:29Published
EU summit: 'I cannot say whether there will be a solution', Merkel says as third day begins [Video]

EU summit: 'I cannot say whether there will be a solution', Merkel says as third day begins

Charles Michel who chairs the summit is expected to reveal new proposals ahead of Sunday's meeting to bridge the gap between the 'frugal four' countries (Austria, Denmark, Netherlands and Sweden) and other countries who don't want to see big cuts and conditions added to the recovery fund.View on euronews

Credit: euronews (in English)    Duration: 01:30Published
Merkel warns of possible EU summit failure [Video]

Merkel warns of possible EU summit failure

European Union leaders may not reach a deal on a coronavirus stimulus plan on Sunday (July 19), German Chancellor Angela Merkel said as marathon negotiations ran into a third day. Francis Maguire reports.

Credit: Reuters - Politics    Duration: 01:33Published
The Netherlands explores an alternative to short-haul flights [Video]

The Netherlands explores an alternative to short-haul flights

The Netherlands aims to be the first to develop the hyperloop and plans to open a European centre in Groningen next year.

Credit: Al Jazeera STUDIO    Duration: 02:51Published

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