In the time of pandemic, 'anti-corona tea', introduced by a local tea seller in Telangana's Warangal, is getting massive public attention.
While speaking to ANI, tea shop owner Shiva said, "We sell tea which is named as 'Anti Corona' as it has natural immunity boosting ingredients like Ginger, Black pepper, Cinnamon Powder and others." One of the customers said that the ingredients used in making the tea boost one's immunity and helps in fighting coronavirus.
A team of chemists from HSE University and the Zelinsky Institute of Organic Chemistry used molecular modelling to find out that two medications that have been known for a long time can be used to fight SARS-CoV-2. These are disulfiram, which is used to treat alcoholism, and neratinib, an experimental drug being used to treat breast cancer. The paper about the discovery has been published online in the 4th issue of Mendeleev Communications journal.The structural elements of the virus that are less subject to mutation during its evolution should be chosen as a target for the potential treatment. Otherwise, a medication effective against one strain would no longer be effective against another. The best candidates for this are conservative proteins, such as the SARS-CoV-2 virus main protease M pro. In addition to being resistant to mutations, M pro plays a major role in coronavirusreplication, which means that its inhibition (blocking its function) is able to slow down or even completely stop its reproduction inside the body.Usually, the process of docking, as with a port dock and a ship entering it, is used for molecular modelling in simple cases. Two molecules participate in docking. One is called a 'ligand' (here, it is a medicine), and the other one is 'receptor' (or active site) of the target protein, such as Mpro, which can be used to 'dock'. An effective drug docks with the active site, by covalent links, which makes the enzyme dysfunctional or destroys it. But classical docking does not work in SARS-CoV-2.To overcome this problem, chemists from HSE University and the Zelinsky Institute decided to use 'on-top docking', which they came up with shortly before the pandemic. 'We decided not to focus on the previously described active site, but to investigate the whole surface of M pro protein with many medications, hoping that the big calculation powers would return useful "dockings",' - said Igor Svitanko, the author of the article,Professor at the HSE Joint Department of Organic Chemistry with the RAS Zelinsky Institute of Organic Chemistry.
White House health experts are warning of a slow rise in the percentage of people testing positive for coronavirus in U.S. cities such as Boston, Chicago, Detroit and Washington and urged local leaders to remain vigilant to avoid a surge. Lisa Bernhard produced this report.
The Covid pandemic has turned out to be a blessing in disguise for this 51-year-old Hyderabad resident. Mohd Nooruddin had failed the 10th board exams 33 times, but he has now benefited from Telangana government's mass promotion scheme in the wake of the Covid pandemic. Mohammad Nooruddin said he had been trying to clear his Class 10th examinations since 1987 but would fail every single time since his English was weak. He said that he used to take help from his cousins for studies but would end up failing every single time. The 51-year-old was ecstatic and said that he had paid the fees for the exams and completed the necessary formalities thinking this will be the last time he appears for the examination. His decision to not give up paid dividends as the Telangana government's decision to not hold exams for class 10 and declare all students passed with minimum marks has made the 34th attempt a success story for Mohammad Nooruddin. Watch the full video to know more about Mohammad Nooruddin's story.
Credit: HT Digital Content Duration: 03:11Published
Cyberabad Police arrested a man on the charges of cheating people on pretext of allocating houses under state government's double bedroom flats scheme. Accused name is Guthula Prashanth and he is the chairman of a TV channel. Police also seized 8 fake flat allotment letters and Rs 8 lakh among other things.
A woman died after the auto she was travelling in lost its balance and felled into overflowing stream in Telangana's Nalgonda. The driver and few others managed to escape from the auto. The streams in Nalgonda district are overflowing due to heavy rainfall from past two days.
Amul Managing Director R.S. Sodhi on June 10 said the milk brand is launching 'Ginger' and 'Tulsi' variants in order to boost community amid the COVID-19. Sodhi reasoned that since a coronavirus vaccine is still to come, their new milk variants will ensure people have enough immunity till then to fight the deadly virus. Amul was recently in news over their Twitter account briefly being restricted over their apparent anti-China post.