United States  

Moderna's COVID-19 vaccine shows early promise

Video Credit: Reuters Studio - Duration: 02:04s - Published
Moderna's COVID-19 vaccine shows early promise

Moderna's COVID-19 vaccine shows early promise

Early data from Moderna''s COVID-19 vaccine showed that it produced protective antibodies in a small group of healthy volunteers.

This report produced by Zachary Goelman.

Promising early results Monday from human trials of a vaccine for COVID-19.

The pharmaceutical company Moderna said its experimental vaccine produced antibodies that could "neutralize" the new coronavirus in patients in a small early stage clinical trial.

The news sent the firm's shares up 25% in early trading Dr. Stephen Hoge is the firm president, and he spoke to CBS News Monday morning about the phase one trial.

"All subjects who had received two doses of our vaccine in the first two dose-level cohorts - that's at 25 microgram, a low-does, and a 100 microgram, our mid dose - had sero-converted to develop antibodies in their blood that bound the virus." Early results from a study by the U.S. National Institues of health showed antibody levels similar to those in blood samples from people who had recovered from COVID-19.

"All together, we're very pleased by that result because it suggests we're on the right path with this vaccine." The drugmaker said the vaccine, mRNA-1273, was also found to be generally safe and well tolerated in the early-stage study.

Hoge said the phase one test was conducted in 45 subjects, and primary focused on the safety of human trials.

Phase two will entail a larger test pool.

"And so we'll be looking across 600 people in the phase two study, which will start any day now, and that will be to both confirm that we've got the right idea of the dose, where we believe we will see protective immunity, as well as, that the safety profile continues to hold up." Dr. Anthony Fauci, the top U.S. infectious diseases expert, last week told Congress the Moderna trial was just one of several currently in development.

"There are at least eight candidate COVID-19 vaccines in clinical development.

I will describe one very briefly, which is not the only one, but one that we have been involved in heavily developing with Moderna (Therapeutrics).

It's a messenger RNA (ribonucleic acid) platform." Moderna leads global efforts in developing a vaccine for the new coronavirus and last week, won the U.S. health agency's "fast track" label to speed up the regulatory review.

It is looking to begin late-stage trials in July.




You Might Like


💡 One News Page Knowledge: Other News Mentions

Moderna Moderna American biotechnology company

Doctors say COVID vaccine's side effects are normal, urge people not to avoid the shots

Ahead of the anticipated distribution of the two-dose coronavirus vaccines from Moderna and Pfizer, medical experts are stressing the importance of getting the..
CBS News

Continuing COVID-19 vaccine trials may put volunteers at unnecessary risk. Is that ethical?

The success of candidate vaccines by Pfizer/BioNTech and Moderna raises ethical questions about continuing placebo trials in which some may get sick.

USATODAY.com

CDC panel says health care workers, nursing home residents should be first to get COVID-19 vaccine

A CDC panel recommended on Tuesday that health care workers and nursing home residents should be first to receive the coronavirus vaccine. Those initial doses..
CBS News

What to expect once FDA approves a COVID-19 vaccine

The first coronavirus vaccines from Pfizer and Moderna could become available by mid-December. Dr. Amesh Adalja, an infectious disease expert and senior scholar..
CBS News

CDC panel votes today on who should be first in line for COVID-19 vaccine

CBS News has obtained a document from Operation Warp Speed that estimates December 15 as the date for states to potentially start receiving the Pfizer vaccine..
CBS News

Coronavirus disease 2019 Coronavirus disease 2019 Disease caused by severe acute respiratory syndrome coronavirus 2

COVID-19 becomes top killer in U.S. as hospitals fill up

Across the country, 100,000 people are in hospitals, and 11 states broke records this week for new cases reported in a single day.
CBS News
Sputnik V: Russia rolls out its COVID-19 vaccination programme [Video]

Sputnik V: Russia rolls out its COVID-19 vaccination programme

Russia has started its COVID-19 vaccination programme, with the first jabs going to workers at high risk of becoming infected with coronavirus.

Credit: Euronews English    Duration: 01:30Published

'A very, very dark place': Hospitals brace for crisis-care mode with too many patients, not enough staff

Hospital ICUs are filled with a record number of critically ill Americans with COVID-19, and there's no relief in sight.

USATODAY.com

COVID-19 surpasses heart disease as leading cause of death in U.S. this week

COVID-19 has surpassed heart disease as the leading cause of death in the U.S. over the last week, as the soaring number of infections overwhelms many of the..
CBS News
COVID-19: Recovery rate stands at 94.5% in UP [Video]

COVID-19: Recovery rate stands at 94.5% in UP

Additional Chief Secretary of Health Department, Amit Mohan Prasad informed that 5,22,866 people have recovered from COVID-19 and discharged till date. The recovery rate is 94.5% and a total of 7900 people have died due to virus till date.

Credit: ANI    Duration: 01:19Published

Anthony Fauci Anthony Fauci American immunologist

Meet Joe Biden's crisis manager, Ron Klain, who will be in the trenches with Dr. Anthony Fauci fighting COVID-19

Ron Klain's chance encounter as a boy with Robert F. Kennedy put him on a path that has led to becoming the top aide to President-elect Joe Biden.

USATODAY.com

Stars and Scars -- You Be the Judge

Well, it looks like some people will get that shot this month, and Dr. Fauci is hopping on the Biden train. So we gotta ask ...
TMZ.com

Dr. Anthony Fauci on "The Takeout" - 12/4/20

Dr. Anthony Fauci, the nation's top infectious disease expert, joins Major for a conversation about U.K.'s approval of COVID-19 vaccines, a vaccine distribution..
CBS News

Fauci walks back U.K. "rushed" approval comments

He said in an interview Friday that his criticism, which first aired on British television, was reactionary, and he "felt badly" about it.
CBS News

Related news from verified sources

Moderna's COVID-19 Vaccine Shows Promise in Early-Stage Study

Moderna, Inc. said on Monday its experimental vaccine for COVID-19 showed promise in early trials and...
Newsmax - Published Also reported by •bizjournalsUSATODAY.comSeattle Times


Moderna CEO: No One Company Can Make Enough Vaccine for Everyone

Moderna, Inc.'s experimental vaccine for COVID-19 is showing promise in early testing, but company...
Newsmax - Published

Moderna climbs 5% as Fauci calls its early COVID-19 vaccine data 'quite promising' (MRNA)

Moderna climbs 5% as Fauci calls its early COVID-19 vaccine data 'quite promising' (MRNA) · *Dr. Anthony Fauci made a series of positive comments about Moderna's early COVID-19 vaccine data...
Business Insider - Published Also reported by •USATODAY.com



Related videos from verified sources

Dr. Fauci Is 'Cautiously Optimistic' About Possibility Of COVID-19 Vaccine [Video]

Dr. Fauci Is 'Cautiously Optimistic' About Possibility Of COVID-19 Vaccine

Researchers working on a vaccine for the novel coronavirus have announced promising results in a very small drug trial. Biotech company Moderna said the first phase of trials for a COVID-19 vaccine..

Credit: Wochit     Duration: 00:32Published
The idea of a vaccine to prevent the novel coronavirus brings mix of comfort and fear [Video]

The idea of a vaccine to prevent the novel coronavirus brings mix of comfort and fear

Health officials have said repeatedly that life won’t go back to the way it used to be until a cure or vaccine to combat the novel coronavirus is created. But not everyone likes the idea of..

Credit: 7News - The Denver Channel     Duration: 05:40Published
Ask Dr. Nandi: Moderna’s coronavirus vaccine shows encouraging early results in human safety trial [Video]

Ask Dr. Nandi: Moderna’s coronavirus vaccine shows encouraging early results in human safety trial

There’s some positive news concerning an experimental vaccine for the coronavirus. Drugmaker Moderna has announced that all of their participants in a stage 1 trial produced antibodies for COVID-19..

Credit: WXYZ Detroit     Duration: 03:19Published